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What is the most important information I should know about losartan?

Do not use this medication without telling your doctor if you are pregnant. Losartan may cause injury and even death of the unborn child if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medicine and inform your doctor immediately if you become pregnant during treatment. You should not use this medication if you are allergic to losartan. Avoid alcohol. It can lower your blood pressure and may increase some side effects of losartan. Do not use potassium supplements or salt substitutes while you are taking losartan, unless your doctor has told you.

To be sure this medication is helping your condition, your blood pressure should be checked on a regular basis. Do not miss appointments.

Continue using this medication even if you feel well. High blood pressure often has no symptoms.

In rare cases, losartan can cause a condition which causes tissue breakdown of skeletal muscles, leading to kidney failure. Call your doctor immediately if you have muscle pain, tenderness or weakness, especially if you also have fever, nausea or vomiting and dark urine.

What should I discuss with my healthcare provider before taking losartan?

You should not use this medication if you are allergic to losartan.

Before using losartan, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease;
• liver disease;

• congestive heart failure, or

• if you are dehydrated.

If you have any of these conditions, you will need a dose adjustment or special tests to take this medication safely.

FDA pregnancy category D. This drug may cause damage to an unborn baby. Losartan may cause injury and even death of the unborn child if you take it during the second and third trimesters of pregnancy. Do not use losartan without consent of your doctor if you are pregnant. Using an efficient form of birth control. Stop using this medicine and inform your doctor immediately if you become pregnant during treatment. It is not known whether losartan is excreted in breast milk or if it could harm the baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

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